The product is an efficient antidote to heparin of equivalent dosage: 1 mg of protamine sulfate neutralizes 1 mg of heparin. The effect occurs instantly (“on the needle”) and lasts for approximately 2 hours. Is usually applied for bleeding due to overdosage of heparin; prior to surgery of patients that take heparin; after heart and blood-system surgery with extracorporeal circulation; after conduction of dialyze.

Solution for injection in 10 ml vials (1000 IU/ml) No 1.